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anti-plectin monoclonal antibody ZB131

A humanized monoclonal antibody directed against human plectin (plectin-1; plectin 1), with potential antineoplastic activity. Upon administration, anti-plectin monoclonal antibody ZB131 specifically binds to plectin expressed on the cell surface of cancer cells, thereby activating the immune system to induce an anti-tumor T-cell response against plectin-expressing cancer cells and inducing apoptosis in these cancer cells. Plectin, a pro-tumorigenic protein, is normally found inside the cytoplasm of healthy cells but is only selectively expressed on the cell surface of various cancer cells. Cancer-specific plectin (CSP), also known as cell surface plectin-1 (CSP1), plays an important role in cancer cell proliferation, migration and invasion.
Synonym:anti-cancer-specific plectin monoclonal antibody ZB131
anti-cell surface plectin 1 monoclonal antibody ZB131
anti-cell surface plectin-1 monoclonal antibody ZB131
anti-CSP monoclonal antibody ZB131
anti-CSP1 monoclonal antibody ZB131
anti-plectin-1 monoclonal antibody ZB131
Code name:ZB 131
ZB-131
ZB131
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