imidazole mustard
A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis.
| Synonym: | HN2 TIC mustard |
|---|---|
| Abbreviation: | BIC |
| Chemical structure: | 5-[3,3-bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide |
| NSC code: | 82196 |