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immediate-release bupropion

An immediate-release (IR) tablet formulation of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation, increasing sexual desire, and reducing cancer-related fatigue. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine, and is a central nicotinic acetylcholine receptor antagonist. Bupropion may also reduce circulating levels of tumor necrosis factor (TNF) and normalize hypothalamic-pituitary-adrenal (HPA) axis functioning, which is dysregulated in certain cases of cancer-related fatigue.

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Synonym:	bupropion immediate release IR bupropion

immediate-release bupropion

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