immunogenic cell death inducer CAN2109

A long-acting, bi-functional immunogenic cell death (ICD) inducer, with potential immunostimulating and antineoplastic activities. Upon intratumoral (IT) administration, ICD inducer CAN2109 may directly kill tumor cells through as of yet undisclosed mechanism of action (MoA). This releases tumor neoantigens, which may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the neoantigens, resulting in tumor cell lysis. CAN2109 retains in the tumor microenvironment (TME) for a long time with minimal release to the systemic circulation after IT administration.