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indicine-N-oxide

A natural pyrrolizidine alkaloid with antineoplastic properties. Indicine-N-oxide alkylates and crosslinks DNA.
Abbreviation:INDI
Chemical structure:2,3-dihydroxy-2-(1-methylethyl)butanoic Acid (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester N-oxide
butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)- (2,3,5, 7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl) methyl ester, N-oxide,(1R-(1.alpha.,7(2R*,3S*),7a.beta))-(9CI)
IND number:13952
NSC code:132319
Search NCI's Drug Dictionary