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indium In 111 FPI-2058

A radioconjugate consisting of the neurotensin receptor type 1 (NTR1; NTSR1) antagonist, IPN01087 (3BP-227) that is linked to the radioisotope indium In 111, with potential imaging activity during single photon emission computed tomography (SPECT)/computed tomography (PET/CT). Upon administration, indium In 111 IPN01087 targets and binds to NTR1 expressed on certain tumor cells. Upon binding and radioimaging, NTR1-expressing tumor cells can be visualized and the biodistribution of IPN01087 can be assessed. NTR1, a G-protein coupled receptor, is highly expressed in ductal pancreatic adenocarcinoma but not in normal pancreatic tissue.
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Synonym:(111In)-IPN01087
[111In]-FPI-2058
111 In-3BP-227
111In-IPN01087
111indium-labeled IPN01087
indium In 111 3BP-227
indium In 111 IPN01087
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