Skip to main content
An official website of the United States government
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

ketoprofen

A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Synonym:capisten
dexketoprofen
US brand name:Orudis
Oruvail
Chemical structure:benzeneacetic Acid, 3-benzoyl-alpha-methyl-
propionic acid, 2-(3-benzoylphenyl)-
propionic scid, 2-(3-benzoylphenyl)-
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search