ketoprofen
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
| Synonym: | capisten dexketoprofen |
|---|---|
| US brand name: | Orudis Oruvail |
| Chemical structure: | benzeneacetic Acid, 3-benzoyl-alpha-methyl- propionic acid, 2-(3-benzoylphenyl)- propionic scid, 2-(3-benzoylphenyl)- |