lebrikizumab
A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and inhibits IL-13-mediated pathways. IL-13, a cytokine mainly secreted by type 2 helper T cells, plays a key role in the induction of allergic inflammation.
| Synonym: | anti-IL-13 humanized monoclonal antibody TNX-650 immunoglobulin G4, anti-(human interleukin 13) (human-mouse monoclonal MILR1444a gamma-4-chain), disulfide with human-mouse monoclonal MILR1444a kappa-chain, dimer monoclonal antibody TNX-650 |
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| Abbreviation: | TNX-650 |
| Code name: | MILR1444A PRO301444 |