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lymphokine-activated killer cells

Killer cell lymphocytes activated in the presence of interleukin-2 (IL-2). Lymphokine-activated killer cells (LAKs) are cytotoxic effector cells with an exceptionally wide target cell spectrum including normal and malignant cells of different origins. LAK cells exhibit a profound heterogeneity with regard to phenotype surface marker expression; it remains to be determined if they represent a unique cell lineage.

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Synonym:	therapeutic lymphokine-activated killer cells
Abbreviation:	LAK LAK cells

lymphokine-activated killer cells

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