Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

Maackia amurensis seed lectin

A preparation of lectin extracted from the seeds of Maackia amurensis, with potential antineoplastic activity. Upon administration, Maackia amurensis seed lectin (MASL) may target and bind to podoplanin (PDPN), thereby blocking the activation of PDPN by endogenous ligands. This may inhibit tumor cell growth, migration and metastasis that result from PDPN activation. PDPN, a transmembrane receptor glycoprotein that is overexpressed in some cancer types, promotes tumor cell migration, invasion, and metastasis upon activation by various endogenous ligands.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Abbreviation:MASL
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search