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methyl bacteriopurpurinimide

A brain-penetrant bacteriochlorin analog and photosensitizer, with potential imaging and antineoplastic activities upon fluorescence imaging and fluorescence-guided photodynamic therapy (PDT) respectively. Upon administration, methyl bacteriopurpurinimide crosses the blood brain barrier (BBB) and is taken up by tumor cells. Upon clinical near-infrared (NIR) imaging, the tumor cells can be detected which allows for visualization of the tumor. Upon NIR PDT, the tumor cells are killed.
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US brand name:Photobac
Chemical structure:3-(1-butyloxy)ethyl-3-deacetyl-bacteriopurpurin-18-n-butylimide methyl ester
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