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mitotane

A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production.
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Synonym:Chloditan
Chlodithane
Khloditan
Mytotan
o,p'-DDD
Ortho,para-DDD
US brand name:Lysodren
Foreign brand name:Lisodren
Abbreviation:DDD
o,p' - DDD
o,p'-DDD
Code name:CB-313
WR-13045
Chemical structure:1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
2-(2-chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane
2,2-bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane
2,4'-dichlorodiphenyldichloroethane
NSC code:38721
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