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monoclonal antibody Lym-1

A murine IgG2a monoclonal antibody directed against the HLA-Dr10 protein, a cell surface marker present on over eighty percent of lymphoma cells. When conjugated with a radioactive isotope, Lym-1 monoclonal antibody selectively transports the cytotoxic radioisotope to HLA-Dr10-expressing tumor cells, thereby sparing healthy B-cells and normal tissues. This agent also mediates antibody-dependent cytotoxicity thereby promoting Raji B-lymphoid cell lysis by human neutrophils.

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Synonym:	IgG2a murine monoclonal antibody Lym-1 Lym-1 monoclonal antibody Lym-1, IgG2a murine
Abbreviation:	MOAB Lym-1
IND number:	3097
NSC code:	620858

monoclonal antibody Lym-1

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