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MUC-1 antigen

MUC-1 antigen is a mammary-type apomucin, a high molecular weight transmembrane glycoprotein, of which the extracellular domain is formed by a repeating 20 amino acid sequence (in tandem) with a high content of serine and threonine on which are O-linked carbohydrate chains. MUC-1 synthesis and secretion are features of glandular epithelial tissues; MUC-1 is overexpressed in lactating breast and in breast, ovary, lung, and prostate malignancies.

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Synonym:	CA15-3 antigen cancer antigen 15-3 DF3 antigen episialin glycosylated MUC-1 ImMucin MUC-1 Muc1 mucin mucin antigen mucin peptide MUC-1 polymorphic epithelial mucin sialylated MUC-1
Abbreviation:	MAM-6

MUC-1 antigen

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