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N-methylformamide

A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells.
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Synonym:formylmethylamine
monomethylformamide
Abbreviation:NMF
Code name:EK 7011
X 188
IND number:20515
NSC code:3051
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