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nemvaleukin alfa

A selective effector cell activator protein and agonist of the intermediate-affinity interleukin-2 (IL-2) receptor with potential immunostimulating and antineoplastic activity. Upon administration, nemvaleukin alfa binds to and signals through the intermediate-affinity IL-2 receptor complex; this may selectively stimulate and activate natural killer (NK) cells and memory CD8 T-cells, leading to tumor cell elimination, while circumventing the activation of immunosuppressive cells that may prevent the anti-tumor response. IL-2 is a cytokine signaling molecule that plays a critical role in the immune response.
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Synonym:Intermediate-affinity IL-2R Agonist ALKS 4230
Intermediate-affinity Interleukin-2 Receptor Agonist ALKS 4230
Code name:ALKS 4230
RDB 1450
RDB-1450
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