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NHS-POx-based hemostatic sealant patch

A sterile resorbable hemostatic sealing patch composed of porcine gelatin fiber-based carrier loaded with N-hydroxy-succinimide polyoxazoline (NHS-POx) polymer and nucleophilically activated polyoxazoline (NU-POx) granulate, with potential hemostatic activity. Upon application on the wound tissue, the coagulation cascade is started. A matrix of platelet aggregation is formed, and a fibrin clot is formed in the gelatin fibers. This combines with NHS-POx and NU-POx to form POx-hydrogel, which promotes hemostasis.

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Synonym:	GATT-Patch

NHS-POx-based hemostatic sealant patch

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