niacinamide
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.
| Synonym: | 3-Pyridinecarboxamide nicotinamide Nicotinamidum Nicotinic Acid Amide Nicotylamide Pellagra-Preventing Factor Vitamin PP |
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| Foreign brand name: | Nicamid Nicosedine |
| NSC code: | 27452 |