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niacinamide

The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.

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Synonym:	3-Pyridinecarboxamide nicotinamide Nicotinamidum Nicotinic Acid Amide Nicotylamide Pellagra-Preventing Factor Vitamin PP
Foreign brand name:	Nicamid Nicosedine
NSC code:	27452

niacinamide

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