nogapendekin alfa inbakicept-pmln
View Patient InformationA mutated form of the cytokine interleukin (IL)-15 (IL-15N72D), with potential immunomodulating and antineoplastic activities. Upon administration, nogapendekin alfa binds to the IL-15 receptor on natural killer (NK) and CD8+ T lymphocytes, which activates and increases the levels of NK cells and memory T cells. This may increase tumor cell killing and decrease tumor cell proliferation. IL-15 regulates CD8+ T and NK cell development, activation and proliferation.
| Synonym: | IL-15N72D-IL-15RaSU/Fc inbakicept nogapendekin alfa fusion complex nogapendekin alfa inbakicept superagonist interleukin-15:interleukin-15 receptor alphaSu/Fc fusion complex Alt-803 |
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| US brand name: | Anktiva |
| Abbreviation: | IL-15N72D/IL-15Ra-Fc |
| Code name: | ALT 803 ALT-803 ALT803 N 803 N-803 N803 |