norepinephrine, DL-
A synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action.
| Synonym: | (+/-)-noradrenaline arterenol noradrenaline Norepinenrine |
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| Chemical structure: | (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol 1,2-benzenediol, 4-(2-amino-1-hydroxyethyl)-, (+/-)- |
| NSC code: | 294898 |