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oglufanide disodium

The disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections.

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Synonym:	glufanide disodium oglufanide sodium thymogen
Code name:	IM 862
Chemical structure:	L-tryptophan, L-alpha-glutamyl-, disodium salt

oglufanide disodium

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