omalizumab
A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor.
| Synonym: | anti-IgE monoclonal antibody E25 olizumab |
|---|---|
| US brand name: | Xolair |
| Abbreviation: | rhuMAb-E25 |
| Code name: | IGE 025 |