oncolytic vaccinia virus OVV-01
An oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration of the oncolytic vaccinia virus OVV-01, the virus preferentially targets and infects tumor cells, thereby causing oncolysis. In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which induce an immune response against the tumor cells. This further kills tumor cells.
Synonym: | oncolytic virus OVV-01 |
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Code name: | C045 OVV 01 OVV-01 OVV01 |