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oncolytic Vaccinia virus PF-07263689

An engineered oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic activities. Upon administration of oncolytic VV PF-07263689, the virus preferentially targets and infects tumor cells, thereby causing oncolysis. In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which induce an immune response against the tumor cells. This further kills tumor cells.
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Synonym:oncolytic VV PF-07263689
Code name:PF 07263689
PF07263689
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