Skip to main content
An official website of the United States government
Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

oncolytic vesicular stomatitis virus

A recombinant form of oncolytic vesicular stomatitis virus (VSV), with potential immunomodulating and antineoplastic activities. Upon administration, oncolytic VSV preferentially replicates in tumor cells. This induces VSV-mediated cytolytic activity towards the tumor cells. VSV, a single-stranded RNA virus belonging to the genus Vesiculovirus of the family Rhabdoviridae, is relatively nonpathogenic to healthy humans but is able to rapidly replicate in and induce apoptosis of tumor cells.
Synonym:oncolytic VSV
US brand name:Revottack
Search NCI's Drug Dictionary