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partially engineered T-regulatory cell donor graft TRGFT-201

A T-regulatory (Treg) cell donor graft that has been partially engineered by depleting all the T cells and then enriching the graft with infusions of conventional T-cells, Tregs and CD34+ stem cells derived from peripheral blood from either related or unrelated matched donors, with potential immunomodulating activity. Upon administration of the partially engineered T-regulatory cell donor graft TRGFT-201 following myeloablation, the allograft may induce tolerance in patients undergoing allogeneic hematopoietic stem cell transplantation (AHSCT) as treatment for hematologic malignancies.
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Synonym:partially engineered and enriched Treg donor graft TRGFT-201
T-cell-depleted graft with additional infusion of conventional T cells and regulatory T cells
US brand name:Orca-T
Code name:TregGraft
TRGFT 201
TRGFT-201
TRGFT201
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