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pazopanib hydrochloride

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The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.
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US brand name:Votrient
Foreign brand name:Pazopater
Code name:GW786034B
Chemical structure:5-((4-((2,3-dimethyl-2h-indazol-6-Yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride
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