pegfilgrastim

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A long-acting pegylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Conjugation of the cytokine with a branched polyethylene glycol molecule (pegylation) significantly increases its therapeutic half-life.

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Synonym:	filgrastim SD-01 pegfilgrastim biosimilar HSP-130 pegfilgrastim biosimilar Nyvepria pegfilgrastim biosimilar Pegcyte pegfilgrastim biosimilar PF-06881894 pegfilgrastim biosimilar Udenyca pegfilgrastim biosimilar Ziextenzo pegfilgrastim-apgf pegfilgrastim-bmez pegfilgrastim-cbqv pegfilgrastim-jmdb pegylated G-CSF pegylated GCSF pegylated granulocyte colony stimulating factor SD-01 SD-01 sustained duration G-CSF tripegfilgrastim
US brand name:	Fulphila Neulasta Nyvepria Udenyca Ziextenzo
Foreign brand name:	Dulastin Jinyouli Neulastim Neupopeg Pegcyte
Code name:	HSP-130 PF-06881894

pegfilgrastim

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