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penicillamine

A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis.
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Synonym:D-mercaptovaline
D-Penicillamine
Depamine
US brand name:Cuprenil
Cuprimine
Depen
Perdolat
Sufortan
Foreign brand name:Atamir
Cupripen
Distamine
Kelatin
Mercaptyl
Metalcaptase
Pendramine
Trolovol
Chemical structure:3-mercapto-D-valine
alpha-amino-beta-methyl-beta-mercaptobutyric acid
beta-thiovaline
beta,beta-dimethylcysteine
NSC code:81549
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