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perfosfamide

The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis.

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Synonym:	hydroperoxycyclophosphamide
US brand name:	Pergamid
Abbreviation:	4-HC
Chemical structure:	2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide 4-hydroperoxycyclophosphamide 4-Pergamid 4'-hydroperoxycyclophosphamide cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxide cis-4-hydroperoxycyclophosphamide
NSC code:	181815

perfosfamide

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