perfosfamide
The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis.
| Synonym: | hydroperoxycyclophosphamide |
|---|---|
| US brand name: | Pergamid |
| Abbreviation: | 4-HC |
| Chemical structure: | 2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide 4-hydroperoxycyclophosphamide 4-Pergamid 4'-hydroperoxycyclophosphamide cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxide cis-4-hydroperoxycyclophosphamide |
| NSC code: | 181815 |