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perillyl alcohol

A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle.

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Synonym:	dihydrocuminyl alcohol perilla alcohol perillic alcohol perillol
Abbreviation:	POH
Code name:	NEO100
Chemical structure:	(S)-(-)-perillyl alcohol 1-cyclohexene-1-methanol 4-(1-methylethenyl)-1-cyclohexene-1-methanol 4-isopropenylcyclohex-1-ene-1-methanol p-mentha-1,8-dien-7-ol
IND number:	47472
NSC code:	641066

perillyl alcohol

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