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personalized peptides-loaded autologous dendritic cell vaccine

A cell-based personalized cancer vaccine composed of autologous dendritic cells (DCs) loaded with the patient’s own tumor-specific peptides, with potential immunostimulatory and antineoplastic activities. Upon administration of the personalized peptides (PEP)-loaded autologous DC vaccine, the DCs activate natural killer cells (NKs) and stimulate a cytotoxic T-lymphocyte (CTL)-mediated immune response against the patient’s tumor cells expressing the PEPs, resulting in tumor cell lysis.

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Synonym:	autologous dendritic cell vaccine loaded with personalized peptides PEP-DC vaccine PEP-loaded autologous DC vaccine

personalized peptides-loaded autologous dendritic cell vaccine

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