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petadeferitrin

An orally bioavailable iron-chelating agent and derivative of desferrithiocin, with iron chelating and protective activities in diseases of iron overload. Upon oral administration, petadeferitrin targets, binds to and chelates free iron. This induces the excretion of iron, prevents iron accumulation and prevents cellular and/or tissue damage associated with iron overload.

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Synonym:	chelating agent SP-420 iron chelating agent SP-420 iron chelator SP-420
Code name:	SP 420 SP-420 SP420
Chemical structure:	(4S)-4,5-dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic acid

petadeferitrin

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