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pixantrone dimaleate

The dimaleate salt of a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity.

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Synonym:	pixantrone maleate
Foreign brand name:	Pixuvri
Code name:	BBR 2778
Chemical structure:	6,9-bis((2-Aminoethyl)amino)benzo(g)Isoquinoline-5,10-dione (2z)-but-2-enedioate (1:2) benz(g)isoquinoline-5,10-dione, 6,9-bis((2-aminoethyl)amino)-, (2Z)-2-butenedioate (1:2)

pixantrone dimaleate

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