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human papillomavirus 16 E7 peptide

A synthetic peptide sequence of human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas.

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Synonym:	HPV-16 E7 HPV16 E7

human papillomavirus 16 E7 peptide

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