PSMA-targeting fluorescent imaging agent IS-002
A near-infrared (NIR) fluorescent imaging agent targeting the tumor-associated antigen (TAA) prostate-specific membrane antigen (PSMA), that can potentially be used as a tumor-selective fluorescent imaging agent during NIR fluorescence imaging-guided surgery. Upon intravenous administration, the PSMA-targeting fluorescent imaging agent IS-002 targets and binds to PSMA on PSMA-expressing tumor cells. Upon fluorescent imaging, PSMA-expressing tumors can be visualized and identified, and surgically removed. PSMA is overexpressed by most prostate cancers.
| Synonym: | fluorophore IS-002 PSMA-targeted fluorescent imaging agent IS-002 |
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| Code name: | IS 002 IS-002 IS002 |