pyrazoloacridine
A 9-methoxy acridine compound containing a reducible 5-nitro substituent. Pyrazoloacridine appears to intercalate into DNA and inhibit RNA synthesis, DNA synthesis, and the activities of topoisomerases I and II, thereby causing cytotoxicity.
| Abbreviation: | PZA |
|---|---|
| IND number: | 36325 |
| NSC code: | 366140 |