pyrazoloacridine
A 9-methoxy acridine compound containing a reducible 5-nitro substituent. Pyrazoloacridine appears to intercalate into DNA and inhibit RNA synthesis, DNA synthesis, and the activities of topoisomerases I and II, thereby causing cytotoxicity.
Abbreviation: | PZA |
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IND number: | 36325 |
NSC code: | 366140 |