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recombinant thyrotropin alfa

A recombinant form of the human anterior pituitary glycoprotein thyroid stimulating hormone (TSH) with use in the diagnostic setting. With an amino acid sequence identical to that of human TSH, thyrotropin alfa binds to TSH receptors on normal thyroid epithelial cells or well-differentiated thyroid cancer cells, stimulating iodine uptake and organification, synthesis and secretion of thyroglobulin (Tg), triiodothyronine (T3), and thyroxine (T4).

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Synonym:	recombinant thyrotropin alpha recombinant TSH alpha thyroid stimulating hormone alpha thyrotropin alfa
US brand name:	Thyrogen
Abbreviation:	TSH-alpha

recombinant thyrotropin alfa

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