rhenium Re 188 etidronate
A synthetic compound containing the bisphosphonate etidronate (hydroxyethylidene diphosphonate, HEDP) labeled with rhenium Re188, a beta-emitting radioisotope with potential antineoplastic activity. Upon administration, Re-188 etidronate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. The beta-radiation may provide localized anti-tumor radiotoxicity while sparing extramedullary bone marrow tissues.
| Synonym: | 188Re-etidronate 188Re-HEDP Re 188 etidronic acid Re 188 hydroxyethylidene diphosphonate Re-188 etidronate Re-188 HEDP Re-188 hydroxyethylidene diphosphonate Re-188etidronate rhenium Re 188-HEDP rhenium Re-188 hydroxyethylidene diphosphonate rhenium-188 etidronate rhenium-188 HEDP rhenium-188-HEDP |
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