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ribocytokine IL-7 BNT152

A formulation consisting of lipid nanoparticles (LNPs) encapsulating nucleoside-modified messenger RNA (mRNA) encoding the endogenous cytokine interleukin-7 (IL-7), with potential immunostimulating activity. Upon administration, ribocytokine IL-7 BNT152 is taken up by cells and the expressed IL-7 targets and binds to the IL-7 receptor (IL7R). The binding of IL-7 to IL7R activates IL7/IL7R-mediated signaling, which activates B and T lymphocytes, may improve immune recovery and activation, and may enhance anti-tumor immune responses.
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Synonym:human interleukin-7 mRNA-encoded BNT152
Code name:BNT 152
BNT-152
BNT152
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