selective estrogen receptor degrader AND019
An orally bioavailable selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD AND019 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells.
| Synonym: | SERD AND019 |
|---|---|
| Code name: | AND 019 AND-019 AND019 |