sodium salicylate
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells.
| Synonym: | salicylate, sodium |
|---|---|
| Chemical structure: | benzoic acid, 2-hydroxy-, monosodium salt |
| NSC code: | 202167 |