sorafenib tosylate
View Patient InformationThe tosylate salt of sorafenib, a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis.
Synonym: | sorafenib |
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US brand name: | Nexavar |
Code name: | BAY 43-9006 tosylate BAY 54-9085 |
Chemical structure: | 4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate tosylate |
NSC code: | 724772 |