allogeneic CD56-positive CD3-negative natural killer cells CYNK-001
A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human placental hematopoietic stem cells (HSCs) and expressing the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating, antineoplastic and antiviral activities. Upon infusion of allogeneic CD56-positive CD3-negative NK cells CYNK-001, these cells are able to recognize tumor cells as well as virally-infected cells, secrete perforins, granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells.
| Synonym: | allogeneic CD56+/CD3- natural killer cells CYNK-001 allogeneic human placental hematopoietic stem cell-derived natural killer cells CYNK-001 CD56+/CD3- NK cells CYNK-001 human placental HSC-derived CD56+/CD3- NKs CYNK-001 natural killer cells CYNK-001 |
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| Code name: | CYNK 001 CYNK-001 |