Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

allogeneic CD56-positive CD3-negative natural killer cells CYNK-001

A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human placental hematopoietic stem cells (HSCs) and expressing the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating, antineoplastic and antiviral activities. Upon infusion of allogeneic CD56-positive CD3-negative NK cells CYNK-001, these cells are able to recognize tumor cells as well as virally-infected cells, secrete perforins, granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells.
Synonym:allogeneic CD56+/CD3- natural killer cells CYNK-001
allogeneic human placental hematopoietic stem cell-derived natural killer cells CYNK-001
CD56+/CD3- NK cells CYNK-001
human placental HSC-derived CD56+/CD3- NKs CYNK-001
natural killer cells CYNK-001
Code name:CYNK 001
CYNK-001
Search NCI's Drug Dictionary