technetium Tc 99m NTP 15-5

A radioconjugate consisting of N-(triethylammonium)-3-propyl-[15]ane-N5 (NTP 15-5), labeled with the gamma-emitting, metastable radioisotope technetium Tc-99 (99mTc), with potential imaging activity upon SPECT (single photon emission computed tomography). Upon administration of technetium Tc-99m NTP 15-5, NTP 15-5 targets and binds to proteoglycans (PGs) present in cartilage extracellular matrix (ECM). This may allow the visualization of cartilage neoplasms and/or cartilage remodeling in arthritis upon imaging.