tetradecanoylphorbol acetate
A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity.
| Synonym: | Lonomycin Phorbol Myristate Acetate |
|---|---|
| Abbreviation: | PMA TPA |
| Chemical structure: | 12-O-tetradecanoylphorbol-13-acetate |
| NSC code: | 61321 |