Skip to main content

Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

thrombomodulin alfa

A recombinant, soluble form of the human protein thrombomodulin, with potential anticoagulant activity. Upon administration, thrombomodulin binds to thrombin, which stimulates the activation of protein C. Activated protein C (APC) degrades factor Va and Factor VIIa in the presence of the cofactor protein S, inhibits thrombin formation, and prevents both thrombin-mediated coagulation and further clot formation.

Check for active clinical trials using this agent View this agent in the NCI Thesaurus

Synonym:	1-498-thrombomodulin (human clone TMP26/TMJ1 protein moiety reduced) recomodulin thrombomodulin (human 498-amino acid fragment)
Abbreviation:	Tma
Code name:	ART 123 ART-123

thrombomodulin alfa

Search NCI's Drug Dictionary