Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

tolazamide

An intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are excreted into the urine. Tolazamide is more potent than tolbutamide and similar in potency to chlorpropamide on a milligram basis. This agent may cause cholestatic jaundice.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
US brand name:Norglycin
Tolinase
Code name:U-17835
Chemical structure:1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea
4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide
NSC code:70762
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search