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tositumomab

A murine IgG2 monoclonal antibody directed against the CD20 antigen, found on the surface of B cells. Tositumomab binds to the CD20 surface membrane antigen, resulting in apoptosis, and may stimulate antitumoral cell-mediated and/or antibody-dependent cytotoxicity.
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Synonym:anti-B1
anti-B1 monoclonal antibody
anti-CD20 antibody
Abbreviation:MOAB anti-B1
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